7/15/2013 · 12.1 Mechanism of Action Kayexalate is a non-absorbed, cation exchange polymer that contains a sodium counterion. Kayexalate increases fecal potassium excretion through binding of potassium in the lumen of the gastrointestinal tract.
Mechanism Of Action KAYEXALATE is a non-absorbed, cation exchange polymer that contains a sodium counterion. KAYEXALATE increases fecal potassium excretion through binding of potassium in the lumen of the gastrointestinal tract .
Pendant l’action de la résine dans les voies intestinales, le sodium est libéré mole pour mole par la capture du potassium. Une dose unique de KAYEXALATE (15 grammes) contient environ 60 mmol de sodium. Étant donné que la résine est une source de sodium, on conseille d’user de prudence quand KAYEXALATE, Sodium polystyrene sulfonate has a delayed onset of action (1 to 2 hours) therefore, the drug is not indicated as an emergency treatment for severe or life-threatening hyperkalemia. Alternative treatment options may include dialysis, insulin with 5% dextrose (15 to 30 minutes), nebulized albuterol (15 to 30 minutes), and intravenous furosemide (15 minutes to 1 hour).[49262].
KAYEXALATE is a cation-exchange resin prepared in the sodium phase, with an in vivo exchange capacity of approximately 1 mmol (in vitro approximately 3.1 mmol) of potassium per gram. The sodium content is approximately 4.1 mmol (100 mg) per gram of the drug. KAYEXALATE can be administered either orally or as an enema. ACTION, Kayexalate – FDA prescribing information, side effects and …
Kayexalate (Sodium Polystyrene): Uses, Dosage, Side …
Kayexalate Uses, Side Effects & Warnings – Drugs.com, Kayexalate – FDA prescribing information, side effects and …
4/4/2019 · Kayexalate can be given as a liquid by mouth, through a stomach feeding tube, or as a rectal enema. Do not give Kayexalate orally (by mouth) to a newborn baby . Do not use the medicine orally or rectally in a baby who has slow digestion.
6/19/2020 · Mechanism of action of Sodium polystyrene sulfonate ( Kayexalate ): Removes potassium by exchanging sodium ions for potassium ions in the intestine (especially the large intestine) before the resin is passed from the body.
Mechanism of Action . Cation exchange resin, sodium ions partially released from polystyrene and replaced by potassium. Absorption. Bioavailability: Nonabsorbable ion-exchange resin. Onset: 2-24 hr. Duration: 4-6 hr. Elimination. Excretion: Feces, 11/14/2019 · Sodium polystyrene sulfonate (Kalexate, Kayexalate , Kionex, SP) is a prescription resin used to reduce high levels of potassium in the blood. Side effects, drug interactions, dosing and storage information, and pregnancy safety information is provided.
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